Promoting Hormonal Health With An Effective Estrogen Management System

DESCRIPTION:

Esteroles AF is a synergistic combination of plant based ingredients including diindolylmethane (DIM), curcumin, green tea, and wasabia designed to support healthy hormone balance and immune health.  DIM is an excellent source to regulate and diminish excessive Estrogen  levels in the body. 

Many women in their twenties, mid thirties through forties, and even women who are menopausal can be overloaded with estrogen.  At the same time they may be suffering from a deficiency of progesterone due to a severe drop in the body’s production, which leads to insufficient progesterone to counteract the amount of estrogen in the body.  It is most noticeable among peri-menopausal women who do not ovulate, which is quite common.  You may have a fairly normal cycle, but no egg is released and very little progesterone is produced.   Even if a woman has low estrogen levels, she can have symptoms of estrogen dominance, because she may have little or no progesterone.  However, estrogen dominance can be caused by more than the body’s production of hormones.  For example, hormone replacement therapy (HRT), birth control pills, environmental estrogens, plant estrogens, stress, obesity, poor liver function, peri-menopause, and glandular dysfunction. 

 The end result of an imbalance between estrogen in relation to progesterone adds up to a condition Dr. John Lee has termed “estrogen dominance.”  Dr. Lee’s books, What Your Doctor May NOT Tell You About Premenopause and What Your Doctor May NOT Tell You About Menopause explains this and more, in-depth.  These books are available on Amazon.

During the body’s natural detoxification processes, potentially detrimental molecules such as hormone metabolites, alcohol, drugs and air pollutants are removed from the blood stream via the liver. Healthy hormone detoxification is a crucial part of the normal functioning of the immune system.  

Diindolylmethane (DIM) is one molecule known for the supportive role it plays in stimulating natural detoxification enzymes and supporting normal hormone metabolism.  For centuries, people have known that cruciferous vegetables - broccoli, brussels sprouts, cabbage, and cauliflower - have value as medicinal plants. But only recently has modern science pinpointed the specific activity of individual cruciferous phytonutrients, especially diindolylmethane (DIM).  As a natural component derived from indole-3-carbinole and cruciferous vegetables, DIM has shown in studies to support the 2-hydroxylation instead of 16-hydroxylation of certain estrogen metabolites. This favors the production of 2-hydroxysterone over the more deleterious 16-hydroxyestrone. Other studies indicate that DIM may play important roles in inducing apoptosis and supporting the body’s normal angiogenic balance. 

Scientists have identified numerous phytochemicals including polyphenols, methylxanthines, flavonoids, and triterpenoid saponins in green tea. The polyphenols contained in tea, specifically the catechins, appear to provide the primary health promoting benefits associated with green tea consumption. Catechin, epicatechin, epigallocatechin (EGC), and most notably EGCG, epigallocatechin gallate act as antioxidants and support immune function, cardiovascular health and hormone detoxification. Additionally, in vitro, these nutrients have been shown to support healthy cell growth and division.  

Studies have shown that curcumin, a naturally occurring biologically active group of compounds from Curcuma longa (Turmeric), can function as efficient antioxidants and can help regulate the body’s normal response to inflammatory processes. Curcumin can also play an important role in maintaining healthy angiogenic balance and help to support the body’s detoxification processes.  Wasabia, a member of the cruciferous vegetable family, contains long chain isothiocyanates (ITCs). These ITCs are believed to be 10-25 times more potent in the detoxification process than most ITCs found in cruciferous vegetables. These long chain ITCs are unique to wasabia and are not commonly found in other cruciferous vegetables. This formula also included Bioperine pepper extract for enhanced absorption.

INDICATIONS: 

Estroles AF may be a useful dietary supplement for individuals wishing to support healthy hormone detoxification.  

Adults take 2 capsules daily or as directed by your healthcare professional.

SIDE EFFECTS: No adverse side effects reported.

Bottle Size: 

 60 Vegetarian Capsules (Store in a cool, dry place, away from direct light. Keep out of reach of children.) 

 REFERENCES

1.        Bonnesen C, Eggleston IM, Hayes JD. Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines. Cancer Res 2001 Aug 15;61(16):6120-30.

2.        Chen DZ, Qi M, Auborn KJ, Carter TH. Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. J Nutr 2001 Dec;131(12):3294-302.

3.        Dalessandri KM, Firestone GL,

4.        Fitch MD, Bradlow HL, Bjeldanes LF. Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. Nutr Cancer. 2004;50(2):161-7.

5.        Fujiki H et al. Cancer inhibition by green tea. Mutat Res 1998;402(1-2):307-10.

6.        Maheshwari RK, Singh AK, Gaddipati J, Srimal RC. Multiple biological activities of curcumin: A short review. Life Sci. 2006 Jan 12  

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.