Clinical studies show that folate, vitamin B12, and vitamin B6 are vital in the metabolism of homocysteine. Vitamin B12 and folate are required by the enzyme that converts homocysteine back to methionine. Vitamin B6 is required in each of the two enzymatic reactions that convert homocysteine to cysteine. Betaine, in the form of trimethylglycine, is included in this supplement to promote the absorption of these important nutrients. Homocysteine Support™ provides vitamin B6, vitamin B12, folate and betaine, a highly bioavailable combination of nutrients integral to supporting normal homocysteine levels and cardiovascular health. As part of a well-balanced diet that is low in saturated fat and cholesterol, folic acid, vitamin B6, and vitamin B12 may reduce the risk of vascular disease. † †FDA evaluated the above claim and found that while it is known that diets low in saturated fat and cholesterol reduce the risk of heart disease and other vascular diseases, the evidence in support of the above claim is inconclusive. REFERENCE: Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial. JAMA 2002 Aug 28;288(8):973-9. Most people who have heart attacks do not have high cholesterol! That's because there's another major cause of heart disease: homocysteine. Medical experts are convinced high homocysteine levels are as dangerous as cholesterol which is why doctors are now treating these high levels with Folic Acid, B-6 & B-12 vitamins. Their studies have proven over and over that the lower your homocysteine, the lower your risk of serious illnesses such as heart disease and Alzheimer's disease.
Not only have large human trials linked high homocysteine with a dramatically greater risk of heart problems, but more recent studies associate high homocysteine with an increased incidence of neurodegenerative issues. (1)
While many doctors and blood laboratories consider homocysteine levels of 5-15 micromoles per liter (mmol/L) blood to be "normal," epidemiologic data indicate that levels above 6.3 mmol/L sharply and progressively increase heart problems.1 One study found that each 3 mmol/L increase in homocysteine caused a 35 percent increase in heart problems.(2)
Referrences: 1. Robinson K, Mayer EL, Miller DP, et al. Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. Circulation. 1995 Nov 15:92(10):2825-30. 2. Verhoef P, Stampler MJ, Buring JE, et al. Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate. Am J Epidemiol. 1996 May 1; 143(9):845-59.
Trimethylglycine (TMG), vitamins B6, B12 and folic acid helps support the conversion of homocysteine to other substances, including methionine, thus preventing and unwanted build-up of homocysteine.
People who take folic acid may increase the chances that arteries will respond to the body's call for more oxygen-rich blood, a step that could reduce the risk for heart attack and stroke, according to the results of a small study. Folic acid, also known as folate, is a B vitamin. Previous research has shown that folic acid helps reduce levels of homocysteine, an amino acid associated with increased risk of stroke and heart disease.
Ingredients: - Trimethylglycine 1,000 mg
- Folic Acid 800 mcg
- Vitamin B-12 500 mcg
- Vitamin B-6 50mg
Other ingredients are cellulose, water, (may contain one or more of the following; magnesium stearate, vegetable stearin and silica).
Usage: - 2 vegetarian capsules daily
Each bottle contains: NOTE: These statements have not been evaluated by the USA Food and Drug Administration. These statements and the product are not intended to diagnose, treat, cure or prevent any disease. Consult your professional health care provider. | 
