Effective Joint Formulation For Joints, Muscles and Ligaments

Limberal AF contains a synergistic combination of glucosamine, chondroitin, astaxanthin  and me thylsulfonylmethane (MSM). Glucosamine HCl is a well-absorbed source of glucosamine, an important precursor for the synthesis and maintenance of connective tissues. Chondroitin sulfate also supports formation of connective tissues, primarily joint cartilage, and helps protect existing cartilage. MSM, a derivative of DMSO, is a naturally occurring compound of biologically available sulfur. Astaxanthin is a natural carotenoid that can help modulate the body’s normal inflammatory response.

"I usually do not write testimonials but with your products I am making an exception. I am 63 years old with arthritis in both knees and have tried just about everything that I could find. I have now been on your Limerbal AF, Wobenzym N and LoPain AF for the past month and have finally found relief from my pain and stiffness which is great as I have several grandchildren that I like to play with. I am going to tell every one of my friends about your great products and company. Thank you for developing products that truly work."

Submitted by: Ann M. - Denver, CO
Dated: 11/10/2008

Our Price $49.95
Retail Price $58.95

FUNCTIONS:

Glucosamine is a naturally occurring amino sugar found ubiquitously in glycoproteins and glycosaminoglycans. Glycosaminoglycans, formerly named mucopolysaccharides, are an integral component of all connective tissues. Connective tissue, a fibrous type of body tissue, has various functions. It supports and connects internal organs (ligaments), forms bone, cartilage, and the walls of blood vessels, attaches muscles to bones (tendons), and replaces tissues that have been damaged following injury. Chondroitin sulfate, a glycosaminoglycan formed in the body, is also used for the synthesis and maintenance of connective tissue, primarily within the cartilage matrix. In addition, chondroitin sulfate protects existing cartilage by reducing water loss from the matrix and by inhibiting the enzymatic breakdown of the cartilage.  

Sulfur is an indispensable element in human nutrition. As part of the amino acids methionine and cysteine, sulfur is required for the structural integrity and function of almost every protein in the body, including enzymes, serum proteins, and the keratin of skin, hair, and nails. Taurine, another sulfur-containing amino acid is known for its role in bile salt synthesis, cell membrane stability, neuronal excitability and the regulation of osmotic pressure. Sulfur is also an essential element for the glycosaminoglycans of connective tissues and cartilage, and assumes a major role in detoxification as part of the hepatic sulfur conjugation pathways. Proper detoxification of xenobiotics, such as phenols, and many endogenous and foreign food- or air-borne compounds depends on an adequate supply of biologically active sulfur.

Dietary MSM serves as a versatile donor of metabolically active sulfur for the synthesis of numerous organosulfur compounds and proteins in the body. As such, MSM helps maintain normal immune response, lung function, connective tissue metabolism, and muscle contraction. The degradation of arachidonic acid to certain leukotrienes and prostaglandins via the cyclooxygenase and lipoxygenase pathways can cause an imbalance in normal inflammatory markers. By inhibiting the enzymatic activity of certain pro-inflammatory cytokines such as cyclooxygenase, the body’s normal response to inflammatory markers can be moderated.

Research indicates that astaxanthin, a natural carotenoid, may play an important role in the moderation of the body’s normal inflammatory response. Human studies also have reported its usefulness in maintaining normal joint and connective tissue structure and function. As a powerful antioxidant, it also can help protects cells from oxidative and free radical damage.

INDICATIONS:

Limberal AF may be a useful dietary supplement for individuals wishing to support normal joint and connective tissue structure and function.

FORMULA :

3 Tablets Contain:

Calcium (dicalcium phosphate) ..................275 mg

Phosphorus (dicalcium phosphate) ............ 240 mg

Glucosamine HCl ..................................... 1500 mg

Chondroitin Sulfate .................................. 1200 mg

Methylsulfonylmethane (MSM^®) ................. 500 mg

Astaxanthin ................................................... 1 mg

SUGGESTED USE

SIDE EFFECTS

BOTTLE SIZE

REFERENCES

1. Böhmer D, Ambrus P, Szögy A, and Haralambie G. Treatment of chondropathia patellae in young athletes with glucosamine sulfate. In: Current Topics Sports Medicine (Bachl N et al., eds.) Urban & Schwarzenberg, Vienna, 1984, p.799.
2. Crolle G, and D’Este E. Glucosamine sulfate for the management of arthrosis: a controlled clinical investigation. Curr. Res. Med. Opin. 1980; 7:104.
3. D’Ambrosio E, Casa B, Bompani R, Scali G, and Scali R. Glucosamine sulfate: a controlled clinical investigation in arthrosis. Pharmatherapeutica 1981; 2:504.
4. Drovanti A, Bignamini AA, and Rovati AL. Therapeutic activity of oral glucosamine sulfate in osteoarthritis: a placebo-controlled double-blind investigation. Clin. Ther. 1980; 3:260.
5. Engel M, Maurel P, Margolis RK .Chondroitin sulfate proteoglycans in the developing central nervous system. I. Cellular sites of synthesis of neurocan and phosphacan. J Comparative Neurology 1996;366:34-43.
6. Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM. Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation. Mol Cells. 2003 Aug 31;16(1):97-105.
7. Lopes Vaz A. Double-blind clinical evaluation of the relative efficacy of ibuprofin and glucosamine sulfate in the management of osteoarthrosis of the knee in outpatients. Curr. Res. Med. Opin.1982; 8:145
8. Morton JI, Siegel BV. Effects of oral dimethyl sulfoxide and dimethyl sulfone on murine autoimmune lymphoproliferative disease. Proc Soc Exp Biol Med 1986;183:227-230.
9. Nir Y, et al. Effect of an astaxanthin containing product on rheumatoid arthritis. Journal of the American College of Nutrition 2002 October;21(5):490.
10. O'Dwyer PJ, McCabe DP, Sickle-Santanello BJ, Woltering EA, Clausen K, Martin EW, Jr. Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer. Cancer 1988;62:944-948.
11. Pereira RR, Harper WJ, Gould IA. Volatile sulfur compounds in milk. I. Effect of chemical form of sulfur-35 on selective labeling of milk constituents and free sulfur compounds. J Dairy Sci 1966;49:1325-1330.

These statements have not been evaluated by the Food and Drug Administration.

This product is not intended to diagnose, treat, cure, or prevent any disease.

"I usually do not write testimonials but with your products I am making an exception. I am 63 years old with arthritis in both knees and have tried just about everything that I could find. I have now been on your Cox-2, Joint Support and Joint Support Plus products for three months and have finally found relief from my pain and stiffness which is great as I have several grandchildren that I like to play with. I am going to tell every one of my friends about your great products and company. Thank you for developing products that truly works."

Submitted by: Ann M. - Denver, CO
Dated: 4/15/2005

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Our Price $33.95
Retail Price $38.95

In addition to MSM, Geromatrix® Joint Support contains:

• Glucosamine, which assists in the regeneration and lubrication of joint cartilage, thus helping to relieve joint pain
• Boswellia, which naturally supports pain relief without the side effects of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
• Chondroitin Sulfate Complex, which contains salicin for inflammation reduction and pain relief. It is known as "Mother Nature's aspirin" because of its pain relieving ability without the side effects of synthetic aspirin
• Bromelain, known to support the relief of inflammation of the joints by stimulating the immune system
• Turmeric Root, Grape Seed, Quercetin, Ginger and L-Proline, all of which have been used in Europe for ages to help relieve inflammatory arthritis and joint pain. Studies show that Ginger may reduce the prostaglandins that sensitize pain receptors at the nerve endings.

To help support and assist in the complete assimilation of the formula by the body, Geromatrix® Joint Support also contains Vitamin C, Niacin, Manganese and Pantothenic Acid.

Ingredients:

• Methyl Sul-fonyl Methane (MSM) 100mg
• Glucosamine Sulfate 1000 mg
• Boswellia 100mg
• Chondroitin Sulfate Complex 100mg
• Bromelain 25mg
• Turmeric Root 50mg
• Grape Seed 10mg
• Quercetin 10mg
• Ginger 50mg
• L-Proline 50mg
• Vitamin C 100mg
• Niacin 25mg
• Manganese 10mg
• Pantothenic Acid 25mg

May contain one or more of the following; magnesium stearate, cellulose, vegetable stearin, dicalcium phosphate and silica.

Contains no added sugar, dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors.

Looking for a specific ingredient? See our Ingredient Map.

Usage:

• 3 tablets daily, with meals

Each bottle contains:

• 90 tablets

NOTE: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease